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Note any changes in morning energy, afternoon slumps, or exercise performance

Gastrointestinal disorders: People with stomach or intestinal disorders, such as Crohns disease and celiac disease, may not be able to absorb enough vitamin B12 from food

Comment: Multiple commenters requested that CMS increase the NTIOL ( add-on payment from the current $50 per lens (established in 1999) to between $95.69-$100 for CY 2026, stating that the payment has not been adjusted for over 2 decades despite significant inflation and increased research and development costs associated with bringing new IOL technologies to market

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Homocysteine (tHcy) Another test to help assess true B12 status is homocysteine

Selective NNMT inhibition as a strategy for metabolic disease